Øystein Bruserud Selected Research

Cytopenia

11/2011	Serum levels of endothelium-derived endocan are increased in patients with untreated acute myeloid leukemia.
3/2011	A prospective observational study of the effect of platelet transfusions on levels of platelet-derived cytokines, chemokines and interleukins in acute leukaemia patients with severe chemotherapy-induced cytopenia.
7/2010	Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells.
3/2010	Early pre-engraftment, functional, in vitro responsiveness of T lymphocytes in allotransplanted, acute leukemia patients: proliferation and release of a broad profile of cytokines, possibly predictive of graft-versus-host disease.
6/2007	T cells remaining after intensive chemotherapy for acute myelogenous leukemia show a broad cytokine release profile including high levels of interferon-gamma that can be further increased by a novel protein kinase C agonist PEP005.
8/2006	Reticulated platelets are increased in chronic myeloproliferative disorders, pure erythrocytosis, reactive thrombocytosis and prior to hematopoietic reconstitution after intensive chemotherapy.
8/2004	Functional characterization of T lymphocytes derived from patients with acute myelogenous leukemia and chemotherapy-induced leukopenia.
5/2004	Cellular immune responses in multiple myeloma patients with treatment-induced cytopenia early after high-dose chemotherapy and autologous peripheral blood stem cell transplantation.
10/2003	Characterization of clonogenic progenitors in autologous peripheral blood stem cell grafts: evaluation of a simple in vitro assay suitable for routine clinical use.
10/2003	Functional evaluation of proliferative T cell responses in patients with severe T lymphopenia: characterization of optimal culture conditions and standardized activation signals for a simple whole blood assay.

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Øystein Bruserud Research Topics

Disease

87	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 01/2002
35	Neoplasms (Cancer) 01/2021 - 05/2004
27	Leukemia 01/2022 - 01/2002
16	Hematologic Neoplasms (Hematological Malignancy) 06/2022 - 05/2004
13	Cytopenia 11/2011 - 06/2002
11	Graft vs Host Disease (Graft-Versus-Host Disease) 04/2022 - 03/2010
8	Inflammation (Inflammations) 06/2022 - 02/2012
8	Infections 01/2022 - 07/2006
6	Acute-Phase Reaction 01/2022 - 09/2002
5	Chromosome Aberrations (Chromosome Abnormalities) 03/2015 - 02/2002
4	Multiple Myeloma 01/2020 - 05/2004
3	Hematologic Diseases (Blood Diseases) 06/2022 - 01/2015
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 05/2019 - 05/2003
3	Venous Thrombosis (Deep-Vein Thrombosis) 01/2019 - 07/2015
3	Thrombosis (Thrombus) 01/2019 - 07/2015
3	Thrombocytopenia (Thrombopenia) 01/2019 - 08/2006
3	Carcinogenesis 10/2017 - 12/2007
3	Bronchiolitis Obliterans Syndrome 01/2017 - 08/2014
3	Weight Gain 11/2016 - 01/2010
3	Bone Marrow Failure Disorders 10/2013 - 10/2004
3	Bacterial Infections (Bacterial Infection) 11/2011 - 09/2002
3	Sarcoma (Soft Tissue Sarcoma) 01/2005 - 04/2004
3	Leukopenia 11/2004 - 10/2002
2	Cytokine Release Syndrome 01/2022 - 11/2021
2	Fever (Fevers) 11/2021 - 10/2018
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2021 - 07/2020
2	Disease Progression 01/2021 - 12/2018
2	Neoplasm Metastasis (Metastasis) 01/2021 - 12/2020
2	Philadelphia Chromosome 05/2019 - 01/2018
2	Sepsis (Septicemia) 01/2018 - 11/2011
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2018 - 01/2018
2	Myeloproliferative Disorders (Myeloproliferative Disorder) 01/2018 - 08/2006
2	Fibrosis (Cirrhosis) 01/2018 - 10/2013
2	Lymphopenia (Lymphocytopenia) 12/2008 - 10/2002
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 02/2006 - 02/2006
2	Febrile Neutropenia 10/2002 - 06/2002
1	Anemia 01/2022
1	Genomic Instability 01/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Psychotic Disorders (Schizoaffective Disorder) 12/2021
1	Mediastinal Emphysema (Pneumomediastinum) 10/2021
1	Pancytopenia 01/2021
1	Neutropenia 01/2021

Drug/Important Bio-Agent (IBA)

26	CytokinesIBA 12/2021 - 05/2003
14	Biological ProductsIBA 01/2022 - 12/2007
13	Proteins (Proteins, Gene)FDA Link 03/2021 - 07/2004
12	Biomarkers (Surrogate Marker)IBA 10/2020 - 02/2013
10	Interleukin-6 (Interleukin 6)IBA 04/2022 - 01/2010
8	Valproic Acid (Depakote)FDA LinkGeneric 05/2021 - 01/2006
7	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2021 - 01/2006
6	ChemokinesIBA 01/2016 - 07/2006
5	Phosphotransferases (Kinase)IBA 01/2019 - 02/2006
5	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2017 - 01/2002
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2011 - 07/2004
4	C-Reactive ProteinIBA 01/2022 - 07/2020
4	Sirolimus (Rapamycin)FDA Link 01/2019 - 03/2008
4	Histone Deacetylase InhibitorsIBA 02/2013 - 09/2007
3	AntibodiesIBA 11/2021 - 02/2010
3	Protein Isoforms (Isoforms)IBA 01/2021 - 04/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2020 - 06/2007
3	ProteomeIBA 03/2020 - 11/2016
3	Immunomodulating AgentsIBA 01/2020 - 01/2019
3	Interleukin-8 (Interleukin 8)IBA 10/2018 - 04/2004
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 09/2018 - 03/2010
3	Metalloproteases (Metalloproteinases)IBA 01/2018 - 07/2015
3	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2009 - 12/2002
2	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 04/2022 - 01/2021
2	Therapeutic UsesIBA 05/2021 - 12/2007
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 07/2020 - 07/2020
2	InterleukinsIBA 07/2020 - 03/2011
2	Interferon-alpha (Interferon Alfa)IBA 07/2019 - 08/2006
2	Transcription Factors (Transcription Factor)IBA 12/2018 - 12/2007
2	Syk KinaseIBA 01/2018 - 01/2018
2	Tyrosine (L-Tyrosine)FDA Link 01/2018 - 02/2006
2	NucleophosminIBA 12/2016 - 03/2015
2	AntigensIBA 06/2015 - 12/2008
2	ConnexinsIBA 03/2015 - 01/2010
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 08/2014 - 12/2006
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 02/2012 - 09/2002
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 09/2011 - 02/2006
2	Complementary DNA (cDNA)IBA 03/2009 - 05/2006
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 06/2007 - 10/2004
2	Interleukin-2 (IL2)IBA 06/2007 - 10/2002
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2005 - 01/2005
1	LipidsIBA 06/2022
1	SteroidsIBA 06/2022
1	Toll-Like Receptor 4IBA 01/2022
1	Antipsychotic Agents (Antipsychotics)IBA 12/2021
1	Chimeric Antigen ReceptorsIBA 11/2021
1	Chloroquine (Aralen)FDA LinkGeneric 08/2021

Therapy/Procedure

32	Drug Therapy (Chemotherapy) 01/2021 - 06/2002
29	Therapeutics 04/2022 - 01/2002
27	Stem Cell Transplantation 06/2022 - 10/2003
11	Immunotherapy 01/2022 - 10/2002
3	Transplantation 11/2019 - 03/2010
3	Hematopoietic Stem Cell Transplantation 01/2017 - 02/2016
3	Autologous Transplantation 09/2011 - 10/2003
2	Aftercare (After-Treatment) 07/2010 - 02/2002
1	Haploidentical Transplantation 01/2022
1	Punctures 10/2021